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the Perrin Technique

The Perrin Technique    

What's the science behind the technique?

The Perrin Technique is a manual system of diagnosis and treatment that has helped many hundreds of patients with CFS/ME since 1989. 

The Perrin Technique was developed as a result of a chance discovery by Dr Raymond Perrin. 

Dr Perrin believes the link to CFS/ME & fibromyalgia arises from a problem with the drainage system with the Brain and Spinal cord. This may clinically appear from a prior defect to the skull, usually in the frontal/nasal region due to either congenital/ hereditary or traumatic aetiology.

Raymond Perrin's research at the University of Salford in conjunction with the University of Manchester, coupled with hundreds of successful clinical case studies and the latest findings in neurophysiology, has provided strong evidence that CFS/ME involves a disturbance of the drainage of toxins from the brain and the muscles. These poisons often enter the body in the form of viruses, bacteria and other microbes, parasitic infection or due to environmental toxins such as pesticides.

However, many toxins are simply an overproduction of chemicals naturally produced within the body to help the immune system with fighting infections, inflammation and stress. Constant physical and emotional stress can lead to this type of overproduction. The excess of some toxins in the brain and spinal cord should drain out of lymph vessels and be broken down by the body's lymphatic system and liver. CFS/ME patients have a reversed drainage that leads to toxins building up in the central nervous system causing the dysfunction of different parts of the brain and spinal cord. This explains the many different symptoms complained by CFS/ME patients. 

The results of the initial research can be found in the following Peer reviews paper. 

1. Perrin R,N. 1993 Chronica Fatigue Syndrome, a review from the biomechanical perspective. British Osteopathic Journal; Vol.xi.

Recent findings suggest that the Perrin Technique may help reduce fatigue symptoms related to Long Covid patients. Perhaps preventing acute symptoms through early interventions. 

1. Adrian H Heald, Raymond Perrin, Andreas Walther, Mike Stedman, Mark Hann, Annie Mukerhejee, Lisa Riste. 2022. Reducing fatigue-related symptoms in Long Covid-19:a preliminary report of a lymphatic drainage intervention. Cardiovasc Enocrinol Metab; 11 (2). 




You will have a comprehensive consultation with Khush Mandaviya  will  last a total of 90 minutes.

During the consultation, we will discuss the treatment, do a detailed medical history, a questionnaire will be completed, examination of your spine, abdomen, head and lymphatics of the thorax which includes to breast tissue (a chaperone should attend the initial consultation). 

In the case of a diagnosis, you will be given a perrin score out of 10, with 10/10 being perfectly heathy. 


Dr Perrin‘s method is an advanced massage & osteopathic technique using gentle articulations, manipulation, massage and cranial techniques to guide the toxins out of the central nervous system into the lymphatic system, also referred to as "neuro- lymphatic drainage" or "the glymphatic system". Simply since it has been shown to drain toxins from the cells known as the "glia" of the brain to the lymphatics. 

Khush Mandaviya has been personally trained by Dr Raymond Perrin at his clinic based in Manchester, and works alongside him & well known, advanced Perrin Practitioner, Rakhee Mediratta at the London Clinics.  

licensed perrin practitioner


Initial Consultation

The initial consultation will last for at least an hour and a half. You may like to bring a chaperone with you. 

You can expect:

  • Consultation form of an interview 

  • Physical Examination. This will include a breast examination, spinal assessment, gentle palpation of the head and abdomen.

  • A diagnosis will be made based on symptoms and the physical findings of CFS/ME. 

  • Advice & appropriate treatment plan

  • Prognosis given


Second Perrin Appointment

The second appointment will last for at least an hour. You may like to bring a chaperone with you. 

You can expect:

  • Thorough step- by -step demonstration of the home self massage routines; to be done by yourself or partner. 

  • Treatment for 30 minutes

  • Any additional Advice



Perrin technique for ME/CFS, fibre

Treatment will consist of 30 minutes weekly, unless otherwise discussed other options with your practitioner. 

You can expect:

  • Follow up chat 

  • 30 minute treatment

  • Advice

The number of treatments will be determined as per protocol in inital consultation 

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